Liverpool manager Jurgen Klopp confirmed Naby Keita is likely to miss the trip to Huddersfield Town but left the door open for Sadio Mane to feature on Saturday.
Keita picked up a hamstring issue while playing for Guinea as Liverpool's injury problems piled up during the international break.
Mohamed Salah and Virgil van Dijk overcame their fitness issues to train on Thursday, although forward Mane was absent after undergoing hand surgery.
Klopp is yet to decide whether the 26-year-old forward will be involved against Huddersfield, who are yet to register a win in the Premier League this season.
"A few of the boys trained and we have to see how they react," the Reds boss told the media.
"The only thing that's pretty sure is that Naby will not be available. With all the rest, we have to see how it develops."
Netherlands international Van Dijk could come in for close attention from Huddersfield following Ronald Koeman's revelation the defender has been carrying two broken ribs.
Klopp, however, removed any doubt over the key centre-back's readiness for the contest.
"You saw when he went off against Southampton [that something was wrong]. Virgil would not leave the pitch without major problems," the German said.
"I would say it has healed pretty quickly. Footballers very often have to play with some kind of pain. He has no problems with that anymore."
Meanwhile, midfielder Fabinho is "close" to a Premier League debut having surprisingly been overlooked since his arrival from Monaco.
"There's only one reason [he has not played] - because other players fit better in the moment," Klopp added. "I really think about who plays in each position. It will always take time for a new player to close the gap."
|Chelsea remain behind Sarri – David Luiz|
|Southgate hails ´tremendous talent´ Rashford|
|It was a clear goal – Valverde dismisses Barca VAR controversy|
|Rashford can emulate Man United greats Ronaldo and Rooney – Solskjaer|
|Barcelona forward Dembele set for tests on sprained ankle|
|Neymar insists Barcelona and Real Madrid links not ´concrete´|
|Barcelona 3 Leganes 1: Messi and Suarez combine to spare Barca´s blushes|
|Pochettino: Lucas Moura fit for Chelsea clash|
|Ranieri positive on Fulham survival chances despite ´unbelievable´ Spurs loss|
|United Arab Emirates v Kyrgyzstan: Zaccheroni confident in attack|
|South Korea lose Ki to hamstring injury|
|It doesn´t look great - Pochettino to wait on Alli assessment|
|Messi benched as Barcelona face Leganes|
|Dalglish texts me before matches - Van Dijk|
|Iran 2 Oman 0: Jahanbakhsh and Dejagah secure last-eight spot|
|Helloooo u remember me? Nkoudou reminds Spurs fans he exists|
|Japan v Saudi Arabia: Pizzi believes Saudis can upset the odds|
|Fulham 1 Tottenham 2: Winks heads late winner after Alli injury|
|Guardiola demands improvement after Man City win|
|Alonso accepts Chelsea guilty of ´silly mistakes´ in Arsenal defeat|
|Guardiola woke us up - Sane reveals half-time rocket for Man City|
|Thailand 1 China 2: Gao Lin keeps dream alive for Lippi|
|Huddersfield Town 0 Manchester City 3: Danilo, Sterling and Sane on target for ton-up City|
|Allegri: Khedira will be like a new signing for Juventus|
|Manchester City reach 100 goals in 2018-19|
|Australia v Uzbekistan: Leckie´s return is ´like a new signing´, says Arnold|
|Jordan 1 Vietnam 1 (aet, 2-4 on penalties): Keeper Van Lam the shoot-out hero|
|I accept his decision - Gattuso axes Chelsea-bound Higuain|
|PSG midfielder Verratti suffers sprained ankle|
|PSG´s Cavani considering career finale in Uruguay|
|A-League Review: Victory fightback in thriller with Wellington|
|Henry explains foul-mouthed confrontation with Strasbourg´s Lala|
|Emery ´not positive´ over Bellerin injury|
|Sanchez: Man United thriving thanks to Solskjaer|
|Tuchel stunned by PSG´s nine-goal thrashing of Guingamp|
|Modric wants to extend Real Madrid stay|
|Marotta: Icardi will re-sign, Godin wants Inter|
|Real Madrid? You never know what the future holds - PSG´s Mbappe|
|Inter lacked quality in disappointing Sassuolo draw - Spalletti|
|CAF Champions League Review: Simba learn Vita lesson as Sundowns find form|
|Guardiola keen to keep City rhythm and challenge on four fronts|
|For Real Madrid, nothing is impossible - Solari refuses to give up in title race|
|Inter 0 Sassuolo 0: Spalletti´s side labour at sparse San Siro|
|Simeone excited by improving Atleti|
|Sarri questions Chelsea motivation after Arsenal surrender|
|Emery urges Arsenal to find balance after downing Chelsea|
|Koscielny hails Arsenal fighting spirit in Chelsea win|
|Pellegrini: It was not a good idea for Arnautovic to play|
|Iran v Oman: We´re not satisfied yet, says Al Mahaijri|
|Dyche defiant despite offside call|
|Hasenhuttl rates Everton win as Southampton´s best|
|Benitez looking up the table after Schar inspires win over Cardiff|
|RB Leipzig 0 Borussia Dortmund 1: Witsel restores six-point cushion|
|Swansea City 1 Sheffield United 0: McBurnie punishes wasteful Blades|
|Cardiff sign Sala from Nantes for club-record fee|
|Arsenal 2 Chelsea 0: Lacazette and Koscielny fire Gunners to rousing derby win|
|Huesca 0 Atletico Madrid 3: Dominant Atleti keep pressure on Barca|
|Rashford arguably league´s best striker with Kane out - Solskjaer|
|Klopp: Exceptional Salah would have scored even more up front!|
|Suspected ´serious´ Verratti injury leaves Tuchel with mixed emotions|
|We needed to rediscover our best form - Ramos pleased for Real Madrid fans|
|City bought Guardiola four full-backs! - Mourinho aims dig at Man Utd transfer policy|
|Valverde ´not frustrated´ amid De Jong & Vela links|
|Championship Review: Leaders Leeds beaten at Stoke as Villa end Hull run|
|Bournemouth rode their luck, admits Howe|
|Barca boss Valverde calls for clarity on RFEF rules|
|Paris Saint-Germain 9 Guingamp 0: Verratti injured for rampant champions|
|Solskjaer: I´ll remember managing United for the rest of my life|
|Palace win a ´massive relief´ for Liverpool boss Klopp|
|Salah fourth fastest to 50 goals in Premier League history|