Liverpool manager Jurgen Klopp confirmed Naby Keita is likely to miss the trip to Huddersfield Town but left the door open for Sadio Mane to feature on Saturday.
Keita picked up a hamstring issue while playing for Guinea as Liverpool's injury problems piled up during the international break.
Mohamed Salah and Virgil van Dijk overcame their fitness issues to train on Thursday, although forward Mane was absent after undergoing hand surgery.
Klopp is yet to decide whether the 26-year-old forward will be involved against Huddersfield, who are yet to register a win in the Premier League this season.
"A few of the boys trained and we have to see how they react," the Reds boss told the media.
"The only thing that's pretty sure is that Naby will not be available. With all the rest, we have to see how it develops."
Netherlands international Van Dijk could come in for close attention from Huddersfield following Ronald Koeman's revelation the defender has been carrying two broken ribs.
Klopp, however, removed any doubt over the key centre-back's readiness for the contest.
"You saw when he went off against Southampton [that something was wrong]. Virgil would not leave the pitch without major problems," the German said.
"I would say it has healed pretty quickly. Footballers very often have to play with some kind of pain. He has no problems with that anymore."
Meanwhile, midfielder Fabinho is "close" to a Premier League debut having surprisingly been overlooked since his arrival from Monaco.
"There's only one reason [he has not played] - because other players fit better in the moment," Klopp added. "I really think about who plays in each position. It will always take time for a new player to close the gap."
|Rooney deserves special England day - Antonio|
|Messi to return for Argentina next year - General manager Burruchaga|
|Croatia´s Dalic and Modric not out for Spain revenge|
|Gabi, Juanfran hopeful over Oblak´s Atletico future|
|England rookie Wilson not comparing himself to Kane|
|Delph impressed by ´special´ Sancho|
|Bolt may give up on football career despite ´a lot of offers´|
|We´re better than Dortmund – Wagner urges Bayern to respond|
|Martinez hails Hazard leadership|
|Muller going through ´difficult´ period, says Low|
|Rooney wanted to finish career at Manchester United|
|Matuidi: Mbappe has a great personality, like Ronaldo, Messi and Zlatan|
|Mendy undergoes knee surgery|
|Ramos refuses to retaliate after Lovren jibe|
|Qatar pull off shock win over Switzerland|
|Rooney has earned England reward - Sarachan|
|Croatia thrashing means nothing now – Luis Enrique|
|Chelsea and Everton among Arnautovic suitors, claims agent|
|Modric defends Ramos after Lovren comments|
|Southgate hails ´outstanding´ Delph as he talks up England strength in depth|
|No war with Manchester United over Fellaini, insists Martinez|
|Rooney to wear number 10 shirt against USA and receive armband from Delph|
|I don´t feel pressure of Liverpool expectations, claims Klopp|
|Reus and Kroos to sit out Germany´s clash with Russia|
|Van Dijk happy to recommend De Ligt if Liverpool ask|
|Messi is a football alien - Malcom|
|Sky´s the limit for Sancho, says Dortmund team-mate Pulisic|
|Maybe one day - Pulisic open to Premier League move|
|Suso ´proud´ of Real Madrid speculation but happy at AC Milan|
|Betis president convinced Lo Celso will stay|
|Germany face relegation, final spots up for grabs - Nations League state of play|
|James Rodriguez out for several weeks with knee injury|
|Lenglet: No problem with Dembele at Barca|
|Claudio Ranieri´s managerial career in Opta numbers|
|Fellaini gets the chop ahead of 31st birthday|
|Maradona: Solari will not last at Real Madrid|
|Dortmund star Sancho was a Bayern target, confirms Salihamidzic|
|Gerrard enjoying ´buzz´ of management|
|Ranieri honoured to lead ´exceptional´ Fulham squad|
|Solari saw Isco out of shape - Ceballos|
|Ranieri replaces Jokanovic at Fulham|
|Rooney: Kane and Sterling are England superstars|
|Messi will make Argentina return, says Maradona|
|Mourinho is better than Guardiola – Maradona|
|Mbappe plays down Pele comparisons|
|Don´t worry bro – Mendy responds to Trump|
|Asensio: It´s not for me to lead Madrid|
|Rooney ready to enjoy England farewell after pressure of ´Golden Generation´|
|Skriniar discussing new Inter contract, confirms agent|
|Former Barcelona boss Martino named MLS Coach of the Year|
|Udinese appoint Nicola after sacking Velazquez|
|Monaco deny they broke rules regarding youth recruitment|
|Del Bosque, Zidane, Lopetegui - The former Castilla coaches Solari follows into Real Madrid hot seat|
|Ozil rejected ´crazy offers´ from Asia, reveals agent|
|Real Madrid appoint Solari on permanent basis|
|Neuer confident despite concerns over Bayern Munich form|
|Pogba: Coming home to United was the best feeling ever|
|Susanna Dinnage to replace Scudamore as Premier League chief executive|
|Murray commits to Brighton until 2020|
|Rooney rejected chance of pre-World Cup farewell|
|Ozil´s Germany absence a ´pity´, says Sane|
|Rooney: I´ll finish my career in the US|
|Real Madrid confirm Reguilon injury|
|Higuain handed two-match ban for Juve meltdown|
|A year on from Italy failure, Ventura leaves Chievo after four games|
|Recalled Alba denies Luis Enrique bust-up|
|´Unhappy´ Christensen won´t push for Chelsea exit|
|Neymar joining Real Madrid wouldn´t hurt Iniesta|
|Trippier out of England squad with groin injury|
|Former England and Chelsea star Joe Cole retires|